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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C2orf57 All Species: 7.27
Human Site: S246 Identified Species: 40
UniProt: Q53QW1 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53QW1 NP_689827.1 395 41589 S246 P A G S V S P S P G P H E V A
Chimpanzee Pan troglodytes XP_001144481 259 27032 P111 A G S V S P S P G P Y E V A L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852610 375 38742 S227 P S V A P G G S G P P S P G P
Cat Felis silvestris
Mouse Mus musculus Q9DA60 530 56632 S381 P G G S P P H S P D F Y Q V A
Rat Rattus norvegicus Q5U2Y8 436 46491 S288 P A D S P P P S P D S Y Q V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.5 N.A. 48.6 N.A. 31.7 33.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 64.3 N.A. 61.2 N.A. 45.2 48.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 N.A. 20 N.A. 46.6 46.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 N.A. 33.3 N.A. 60 66.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 40 0 20 0 0 0 0 0 0 0 0 0 20 40 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 20 0 0 0 0 0 0 40 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 20 20 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % F
% Gly: 0 40 40 0 0 20 20 0 40 20 0 0 0 20 0 % G
% His: 0 0 0 0 0 0 20 0 0 0 0 20 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 80 0 0 0 60 60 40 20 60 40 40 0 20 0 20 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 20 20 60 20 20 20 80 0 0 20 20 0 0 20 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 20 20 20 0 0 0 0 0 0 0 20 60 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 20 40 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _